"The ability to analyze ancient DNA methylation patterns beyond bones gives us a window into how tissues, especially brain cells ... changes in human evolution and the development of complex ...

Accumulating evidence indicates that epigenetic modifiers have key roles in genome-wide reprogramming and activation and repression of specific genes during mammalian germ-cell development.

Researchers analyze various aspects of gene regulation, among which are the three-dimensional structure of the genome and DNA methylation, which differ for different cell types and play significant ...

“Generally, methylation ... of DNA that have that protein [attached],” said Cosgrove. The recent development of assay for transposase-accessible chromatin with sequencing (ATAC-seq), a simple ...

Labs around the world are trying to turn cells into autobiographers, tracking their own development from embryos ... different organs and tissues in the human body and comprising as many as ...

Two weeks after a human egg is fertilized, primordial germ cells (PGCs), which develop ... at the National Center for Child Health and Development, said the latest research marked a significant ...

It allows researchers to quickly, and cheaply, target and edit genes at precise locations along the lengthy DNA ... to “germ line” cells — those that could pass on edits to a future human.