The type 1 IGF receptor (IGF-IR) is activated by two ligands, IGF-1 and IGF-2, and by insulin at supraphysiological concentrations. It plays a significant role in the growth of normal and abnormal ...
With potential to have lonigutamab as a possible best-in-class anti-IGF-1R drug for TED, plus moving rapidly into phase 3 clinical testing, I believe that investors could benefit with any ...
A list of suggestions for customizing IGF-IR targeting is provided in the Executive summary. One has to seriously consider the hypothesis that cancer cells can acquire the ability of using one ...