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促进癌细胞增殖和迁移!上海交大发文:增强抗肿瘤疗效的候选靶点
【导读】头颈部鳞状细胞癌(HNSCC)是一种极具侵袭性的疾病,其特征在于肿瘤免疫微环境(TIME)的异质性。肿瘤相关巨噬细胞(TAMs)构成了TIME 中的主要先天免疫群体,在恶性肿瘤进展中参与了关键的调节过程。SPP1 + 巨噬细胞(SPP1 + ...
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