The microbiome shapes the development of insulin-producing cells in infancy, leading to long-term changes in metabolism and ...

Type 1 diabetes (also called insulin-dependent diabetes mellitus, or juvenile diabetes), in contrast, usually has an autoimmune T cell-mediated ... in humans and NOD mouse pancreas.

Finally, endocrine cells produce hormones like insulin ... pancreas develops. “The stem cell of the fetal pancreas is present longer than scientists have seen in earlier studies with mice ...

Since these pivotal discoveries, we now know that islets comprise the endocrine portion of the pancreas. Within islets, beta cells secrete insulin ... reported that mouse islets express high ...

First-in-Human Study Provides Evidence that Sana’s Hypoimmune (HIP) Technology Enables Transplanted Islet Cells to Avoid Immune Rejection and ...