Objective—Insulin stimulates brain glucose metabolism, but this effect of insulin is already maximal at fasting concentrations in healthy subjects. It is not known whether insulin is able to ...
“Insulin was discovered 100 years ago, and the insulin receptor was discovered 50 years ago,” Heiko Lickert told BioWorld. “Now we have a new insulin receptor, which degrades insulin.” Lickert is the ...
Together with his team, they discovered Inceptor in 2021 and described its role as an inhibitor of the insulin signaling pathway. The findings are published in the journal Nature Metabolism.
Dysregulation of valine degradation and dysbiosis of B thetaiotaomicron may underlie the relationship between objective EDS and disordered glucose metabolism in OSA. Patients with obstructive sleep ...