The cholesterol-lowering drug ezetimibe (Zetia) has been associated with muscle aches and rhabdomyolysis when used on its own and in combination with statins. Other factors that increase the risk ...

Mechanisms of action Ezetimibe's inhibition of cholesterol absorption results in depletion of the cholesterol in chylomicrons, which in turn leads to diminished hepatic cholesterol and ...

If this is the case, the statin should be stopped. I also read that a drug that shouldn’t affect the muscles at all — ezetimibe (Zetia), which works by reducing absorption of cholesterol from the diet ...

A recent simulation study published in the journal Scientific Reports analyzed representative data of over two million outpatients in Germany, in which the researchers reported that a combination ...

Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates).

That means the contribution for the CETP inhibitor is hard to gauge, but the top-line is well above what has been seen in trials of ezetimibe alone when added to statins and, in any case ...

Menarini Group announces positive topline data from pivotal phase 3 BROADWAY & TANDEM trials of Obicetrapib and FDC Obicetrapib with Ezetimibe 10 mg: Florence, Italy Wednesday, De ...

Mechanisms of action Ezetimibe's inhibition of cholesterol absorption results in depletion of the cholesterol in chylomicrons, which in turn leads to diminished hepatic cholesterol and ...