Translocations, in genetics ... Many important clinical conditions like Down syndrome and chronic myelogenous leukemia result from translocation mutations. A change in chromosome structure ...

Figure 2 shows an example of a spectral karyotype prepared from acute myeloid leukemia cells with multiple translocations, which are indicated by arrows. The image obtained in the microscope ...

Cite this: Recent Advances in the Biology and Management of Primary Acute Myeloid Leukemia with Rearrangements of the MLL Gene - Medscape - May 03, 2000. Strout, MP, Caligiuri, MA, Bloomfield CD.