At this time, recruitment for extended follow-up is complete. Manifestations of the Marfan syndrome appear in many parts of the body, especially in the bones and ligaments (the skeletal system), the ...

The standard treatment for the connective tissue disorder Marfan's syndrome (MFS) is β-blockade, aimed at reducing aortic wall stress. Angiotensin II type 1 and 2 receptors (AT 1 and AT 2 ...

We assessed valve function, aortic size and biventricular measures using echocardiography ... Individuals with a definitive or borderline diagnosis of Marfan syndrome, a positive family history of ...

Loeys-Dietz syndrome ... Marfan syndrome, potentially reducing the risk of vascular tears, early death or the need for surgery. "The new findings could help us better understand why the aortic ...

About one in every 100 people has a bicuspid aortic valve, and half of them have ... of an aneurysm or an aortic dissection ...