纽约大学疼痛研究中心的研究人员发现了一种新的神经生长因子(NGF)受体,尽管它不能独立发出信号,但它在疼痛信号传导中起着关键作用。这些发现发表在《Journal of Clinical Investigation》上,可能为关节炎、炎症性疼痛和癌症疼痛的新疗法铺平道路,解决了以前的治疗方法由于副作用而在临床试验中失败的局限性。
The signaling axis composed of nerve growth factor (NGF) and the receptor tropomyosin-related kinase A (TrkA) is one of the few non-opioid targets that has been validated for treating chronic pain in ...