Substance P is a small peptide of the tachykinin family that is involved in a range of biological processes, predominantly via signal transduction from its highest-affinity receptor, NK1R.
Expert Rev Clin Immunol. 2012;8(3):235-241. Psychosocial stress can exacerbate the psoriatic skin disease in 40–80% of patients, but the mechanism is not clear. Factors induced during stress in ...