In April, 1958, the intermittent steroid therapy was changed to methylprednisolone, 40 mg. daily for 3 consecutive days each week, with some moderate improvement in the nephrotic syndrome.
Nephrotic syndrome is caused by damage to glomeruli (filters) in the kidneys. Symptoms include swelling around the eyes and in the feet and ankles, foamy urine and weight gain due to excess fluid ...