The nucleolus may hold the key. Nucleolus: A Key to Aging and Lifespan Regulation The nucleus contains the cell's chromosomes, while the nucleolus houses the ribosomal DNA (rDNA). The nucleolus ...

Small packages The nucleus holds the cell's chromosomes and the nucleolus where the ribosomal DNA (rDNA) is housed. The nucleolus isolates the rDNA which encodes the RNA portions of the ribosomes ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

This model of the nucleus with nucleolus (pink) shows how ribosomal DNA is correctly repaired in young cells. In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to ...