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Nature | 小环大威力:癌症中的脱缰野马ecDNA(染色体外DNA)
在ecMDM2模型的双阳性细胞中,通过显微镜观察到染色体旁边的小环结构,这些结构代表ecDNA。在50多个细胞中统计,双阳性ecMDM2细胞中的ecDNA数量显著高于invMDM2对照细胞(统计学显著性P < 2.22 × 10⁻¹⁶)。
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