In addition to its effects on purine metabolism, AP, via its metabolite, oxipurinol ribonucleotide, inhibits pyrimidine biosynthesis (PB) at the level of orotidine mono-phosphate decarboxylase.
L-ornithine-L-aspartate (LOLA) is not frequently used as there are still some reservations about its benefits. The present study aimed to assess the effectiveness and safety of LOLA in the ...