Medically reviewed by Lindsay Cook, PharmD Vicodin (hydrocodone-acetaminophen) and Percocet (oxycodone-acetaminophen) are ...

Percocet (acetaminophen and oxycodone) and hydrocodone are two narcotic pain relievers that relieve moderate to severe pain. Both medications are similarly effective at reducing pain. However ...

She was started on low-dose oxycodone with acetaminophen (Percocet 2.5/325) 1 to 2 tablets every 4 hours as needed (≤ 8 per day with instructions to avoid other sources of acetaminophen).