[91] A very recent systematic review published last year has sought the evidence that addresses the role of combination antifungal therapy (mainly azoles with either an echinocandin or a polyene ...

Olorofim (F901318) is the first in a new class of orotomide antifungal agents intended to ... echinocandins, and polyene-based medicines fail. Resistant infections remain rare, but have been ...

Olorofim (formerly F901318) is the first in a new class of orotomide antifungal agents intended ... echinocandins, and polyene-based medicines fail. The FDA granted F2G a breakthrough designation ...