According to a case–control study published in Neurology, the expression of proinflammatory cytokines is elevated in the affected skin of patients with small-fiber neuropathy (SFN).
Figure 1. Cytokines involved in acute and chronic inflammatory responses (DOI:10.2741/a171). Image Credit: Sino Biological Inc. Disturbance in levels of the key pro-inflammatory cytokines ...
Tumor Necrosis Factor-alpha (TNF-α) is a cytokine important in nearly all acute inflammatory reactions by acting as an amplifier of inflammation. TNF-α blockade has been used worldwide to treat ...
T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...