Familial hypercholesterolemia results from gene mutations approximately halving the number of functional LDL receptors in heterozygotes and a greater lack in homozygotes. Reduced receptor-mediated ...

Coronary heart disease (CHD) is a leading cause of morbidity and mortality globally. Hypercholesterolemia is one of the major risk factors for CHD. With the increase in aging populations and ...

Numerous point mutations of the LDLR that result in the genetic disease familial hypercholesterolemia (FH) alter side chains that form conserved packing and hydrogen bonding interactions in the ...

The epidemiology of hypercholesterolemia has been shifting in recent years. The optimal total cholesterol level is defined as about 150 mg/dL, putting low-density lipoprotein (LDL) cholesterol ...

Familial Hypercholesterolemia "The justly celebrated unraveling of the LDL receptor pathway revealed that mutations in a single gene give rise to familial hypercholesterolemia (FH)," Peter Libby ...

Considering taking supplements to treat hypercholesterolemia? Below is a list of common natural remedies used to treat or reduce the symptoms of hypercholesterolemia. Follow the links to read ...

Share on Facebook. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window "Medical Journeys" is a set of clinical resources reviewed ...

Considering taking supplements to treat familial hypercholesterolemia? Below is a list of common natural remedies used to treat or reduce the symptoms of familial hypercholesterolemia. Follow the ...