We now introduce an algorithm called Root Causal Strength using Perturbations (RCSP) that discovers the surrogate ancestors of each variable using Perturb-seq and then computes the RCS of each ...

By Hugo Francisco de Souza Scientists reveal how distinct brain cells contribute to Alzheimer’s progression, unlocking new ...

This application note provides insights into innovative methodologies designed to enhance miRNA discovery and mapping from ...

For many people, RNA entered the consciousness during the race to develop a COVID vaccine. on Tuesday, three researchers who ...

This page provides educational resources, events, news and products related to next-generation sequencing techniques and applications, including sequencing technologies and DNA and RNA-based ...

The current single-cell RNA sequencing technology faces the same challenge when it comes to identifying the genes of interest. Differentially expressed genes can be identified by pooling single ...

Now, Meyer and colleagues have found a way to map m 6 A sites that is compatible with single-cell RNA-Seq. They constructed a chimera comprising the cytidine deaminase APOBEC1 and the YTH binding ...

This valuable paper seeks to determine the role of endogenous CNS hemoglobin in protecting mitochondrial homeostasis in hypoxia. There is merit in the work, although it remains incomplete as there is ...

Researchers have now mapped lncRNA (long non-coding RNA molecules) in human skin wounds in tissue samples from Karolinska University Hospital, identifying a key regulator in wound healing.

研究发现在老年痴呆症患者的大脑中转座子 (TE)普遍失调，可以使用CRISPR干扰等先进技术鉴定TE相关风险基因。研究揭示了这些广泛失调的转座子有可能成为阿尔茨海默病新治疗方法的关键。