The theoretical basis for and clinical experience with using oral serotonin type 3 (5-HT 3)-receptor antagonists for preventing chemotherapy-induced emesis are discussed. Evidence supports the ...
The researchers then decided to test the use of serotonin antagonists as a treatment strategy in mice. “The use of ketanserin, a well-known serotonin receptor 2 blocking drug, proved to be very ...
A surrogate test that may have clinical relevance is the duration of inhibition at 5-HT 3 receptors located on cutaneous afferent neurons. Intradermal injection of serotonin produces a flare ...
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