Serotonin is a neurotransmitter synthesized both peripherally and centrally from dietary amino acid L-tryptophan. Serotonin is produced peripherally by the intestinal chromaffin cells and ...

Serotonin syndrome is a preventable, drug-related complication that results from increased brain-stem serotonin activity, usually precipitated by the use of one or more serotonergic drugs.

Additionally, the recreational use of substances like ecstasy and other illicit drugs can also contribute to serotonin syndrome. The symptoms may include mental status changes, autonomic ...

Cyclobenzaprine HCl 5mg, 7.5mg, 10mg; tabs. Cyclobenzaprine HCl relieves skeletal muscle spasm of local origin without interfering with muscle function. It is ineffective in muscle spasm due to ...

Nearly all current drugs for osteoporosis act by inhibiting ... show that specifically inhibiting biosynthesis of gut-derived serotonin (GDS) can increase bone formation and prevent or reverse ...

increasing the risk of serotonin syndrome. Since St John's wort is a liver enzyme inducer, theoretically this may cause it to breakdown anti-epileptic drugs—such as carbamazepine and phenytoin.

See Contraindications. Do not give with citalopram. Increased risk of serotonin syndrome with other serotonergic drugs (eg, SSRIs, SNRIs, triptans, tricyclic antidepressants, fentanyl, lithium ...

In some cases, taking it with other drugs may lead to serotonin syndrome, which occurs when serotonin levels are too high. For these reasons, healthcare professionals advise people not to use St.