The doctor you are see may suggest you to switch from SSRI to SNRI. While SNRIs enhance both serotonin and norepinephrine ...

Serotonin-norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressants that block the reuptake of both serotonin and norepinephrine in the body. They are taken to treat depression ...

Duloxetine is one of the most commonly used SNRIs in the U.S., often prescribed under the brand name Cymbalta. Duloxetine is also FDA-approved to help treat other conditions, including chronic ...

SNRIs, however, increase both serotonin and norepinephrine. Norepinephrine plays a key role in regulating energy, alertness, and the body’s stress response. This combined effect can provide ...

See Contraindications. Do not give with citalopram. Increased risk of serotonin syndrome with other serotonergic drugs (eg, SSRIs, SNRIs, triptans, tricyclic antidepressants, fentanyl, lithium ...