而新开发的环张力促进的炔烃-叠氮环加成 (SPAAC) 方法具有反应条件温和、操作简便、与核酸适体构象兼容性高的优点，是一种较实用的CBApts合成方法。

Here we look back at one of its key reactions: strain-promoted azide–alkyne cycloadditions (SPAAC). Owing to its robustness, simplicity and applicability to living systems, SPAAC continues to ...