Neuronal atrophy early in a mouse model of spinal cerebellar ataxia 1 may represent an adaptive mechanism that restores the density of potassium channels in Purkinje neurons, thus normalizing ...

Patients with spinocerebellar ataxia type 14 display cerebellar atrophy (right, green arrow) compared to age-matched healthy controls (left). Disclaimer: AAAS and EurekAlert! are not responsible ...

Cerebellar Purkinje cell(PC) impairment cause spinocerebellar ataxiass (SCAs) but there has been few treatments. In this research, we plan to elucidate pathologic pathways from RNA expression to ...

Numerous causes for DBN are known. Familial DBN subsequent to spinocerebellar degeneration is among the most common causes of DBN. In addition to hereditary causes, causes of acquired DBN include ...