AlphaFold solved a structural biology riddle: predicting protein structure. And yet, CASP, a global competition born to solve ...

Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and ...

Protein folding has been an ongoing problem for researchers since 1972. Christian Anfinsen speculated in his Nobel Prize acceptance speech in that year that the three-dimensional structure of a ...

Based on a protein’s three-dimensional surface structure, the algorithm designs molecules that bind specifically to the protein according to the lock- and-key principle, so they can interact ...

"The whole way in which a protein functions is dependent on its three-dimensional structure and protein function is relevant to everything in health and disease. "By knowing the three-dimensional ...

Boltz-1 is the first fully commercially accessible open-source AI model to rival AlphaFold3, DeepMind's latest generative AI ...

which are linked together by peptide bonds and folded into specific three-dimensional structures. Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding ...

This article was originally published with the title “ The Three-Dimensional Structure of a Protein Molecule ” in Scientific American Magazine Vol. 205 No. 6 (December 1961), p. 96 doi:10.1038 ...

Without high quality crystals of a protein, it is impossible to carry out crystallographic structural studies. Using three-dimensional structure information, researchers can determine how proteins ...

so different proteins have different three-dimensional shapes. The three-dimensional shape of a protein determines its function. This is because proteins form attachments and interact with many ...

Proteins are the workhorses of cells. Learn how their functions are based on their three-dimensional structures, which emerge from a complex folding process.