Superior quality cytokines are crucial for reliable research results and the safe production of cancer cell therapies.

Chronically activated proinflammatory cells in the TME contribute to the metastatic ... direct mutational and indirect molecular effects. Cytokines such as IL-6 promote cell transformation by ...

The resulting T cells migrate to the TME where, once they detect their target cells, they either eliminate them directly by cytotoxic lysis or trigger the release of pro-inflammatory cytokines.

The TME may contain inhibitory signals blocking immune responses and lacking cytokines like IL-15, which are essential for optimal T cell function and survival. Four clinical trials were conducted ...

MDNA413 is an IL-13 superantagonist designed to block both IL-4 and IL-13 signaling on tumor cells and in the TME. MDNA413 has ... Superkines can provide a cytokine boost to stimulate effector ...

IL-1 Mediates inflammatory cell accumulation in the TME IL-6 Modifies gene expression ... of reactive oxygen/nitrogen species and cytokines, which contribute to carcinogenesis through mutational ...