Three trimethylsilyl based malonate esters, bis(trimethylsilyl) 2-methyl-2-fluoromalonate (BTMSMFM), bis(trimethylsilyl) 2-ethyl-2-fluoromalonate (BTMSEFM) and bis ...
To obtain the orthogonally protected monosaccharide, trimethylsilyl trifluoromethanesulfonate (TMSOTf) was used as an ideal reagent to catalyze protecting group exchange in the one-pot strategy.
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How cellular metabolic state impacts cellular programs is a fundamental, unresolved question. Here, we investigated how glycolytic flux impacts embryonic development, using presomitic mesoderm (PSM) ...
Cholesterol synthesis is both energy- and oxygen-intensive, yet relatively little is known of the regulatory effects of hypoxia on pathway enzymes. We previously showed that the rate-limiting and ...
We study the fundamental properties of conjugated organic molecules and polymers (plastics) that can be used as organic semiconductors. Such materials are employed with great success today in ...