Naturally rewarding stimuli (i.e. food, sex, etc) increase the activity of dopamine cells in the mesocorticolimbic dopamine system causing increased dopamine release in brain areas such as the nucleus ...

The tag reduced overall dopamine uptake, indicating that hDAT Twin had a lower expression than wild-type hDAT when transiently expressed in COS7 cells. Next, the structure of hDAT Twin bound to ...