Viral infections like COVID-19 can trigger systemic inflammation and may lead to high levels of a chemical called cytokines. This is also known as cytokine release syndrome (CRS) or a "cytokine storm.

Alterations in cytokine expression associated with inflammation have long been observed in individuals with immune-mediated disease. Clinical trials carried out almost a decade ago were the first ...

Cell culture is a cornerstone of modern biological research, offering a controlled and replicable environment for studying cellular processes. Within this context, cytokines and growth factors are ...

Cytokine release syndrome (CRS) is a condition caused by certain medications, treatments, and infections. It happens when a large volume of proteins known as cytokines are suddenly released into ...

Ruxolitinib phosphate is under clinical development by Incyte and currently in Phase III for Coronavirus Disease 2019 (COVID-19) Associated Cytokine Release Syndrome.