Viral infections like COVID-19 can trigger systemic inflammation and may lead to high levels of a chemical called cytokines. This is also known as cytokine release syndrome (CRS) or a "cytokine storm.

Cell culture is a cornerstone of modern biological research, offering a controlled and replicable environment for studying cellular processes. Within this context, cytokines and growth factors are ...

Unexpected findings now identify multiple secreted inflammatory cytokines, their cognate receptors and positive-feedback loops with corresponding transcription factors, as key mediators of both ...

Ruxolitinib phosphate is under clinical development by Incyte and currently in Phase III for Coronavirus Disease 2019 (COVID-19) Associated Cytokine Release Syndrome.