Scientists have discovered that our specialized immune cells, called T cells, are what they eat -- their switch from functional to 'exhausted' depends on the switch from metabolizing acetate to ...

The novel link between nutrition and cell identity offers a new explanation for exhausted T cell identity and in turn, offers ...

Lately, Acetyl L-Carnitine, a known supplement, has attracted increasing attention. This supplement is a byproduct of L-Carnitine, an amino acid naturally present in the human body. Acetyl L ...

Findings reveal that metabolic enzymes ACSS2 and ACLY regulate T cell exhaustion, linking nutrient metabolism to epigenetic ...

Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, ...

or CO 2 to acetate via a unique metabolic pathway in which acetyl coenzyme A (acetyl-CoA) is an intermediate. However, even for acetogens, CO retards growth, so their tolerance to it needs to be ...