Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists. The findings ...

The novel link between nutrition and cell identity offers a new explanation for exhausted T cell identity and in turn, offers ...

Findings reveal that metabolic enzymes ACSS2 and ACLY regulate T cell exhaustion, linking nutrient metabolism to epigenetic ...

or CO 2 to acetate via a unique metabolic pathway in which acetyl coenzyme A (acetyl-CoA) is an intermediate. However, even for acetogens, CO retards growth, so their tolerance to it needs to be ...

See Tayyebi et al. Acetyl-CoA carboxylation is the canonical route for endogenous malonyl-CoA formation in cells. Now, Li et al. report a non-carboxylative malonyl-CoA pathway, independent of ...

Lately, Acetyl L-Carnitine, a known supplement, has attracted increasing attention. This supplement is a byproduct of L-Carnitine, an amino acid naturally present in the human body. Acetyl L ...