Dr. Wakil demonstrated the requirement of ATP and stimulatory effect of carbon dioxide on fatty acid synthesis from acetyl-CoA, and showed that long-chain fatty acids are synthesized by a system ...

During beta-oxidation, fatty acid molecules are broken down by removing two-carbon units from the carboxyl end of a fatty acid molecule to produce acetyl-CoA.

Research in the Abu-Elheiga Lab is focused on the hormonal and dietary regulation of fatty acid metabolism in diseases and adverse health conditions, particularly the contemporary epidemic of obesity ...