They will instead be cytoplasmic hybrids or 'cybrids' 7, where cytoplasm, including mitochondrial DNA (mtDNA), will be combined from the two species, but the genomic DNA will be uniquely human.

The incidence of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis increases with age.1 Despite this trend, ...

随着女性生育年龄的推迟，高龄女性对试管婴儿（IVF-ET）技术的需求日益增长。然而与年轻女性相比，高龄女性在试管婴儿过程中面临的挑战更为复杂和严峻。所以今天林群凡主任就为大家展开谈谈“高龄女性做试管婴儿时最常难题及应用策略”，以帮助高龄女性更好地实现 ...

The type 1 ryanodine receptor (RyR1) is an important calcium release channel in skeletal muscles essential for muscle ...

Microscopic organisms such as bacteria and fungi live together in neighborhoods known as microbial consortia. Some of these ...

Zhijian “James” Chen received this year’s Albert Lasker Award for discovering cGAS, an enzyme which scopes out DNA-based ...

The excessive cosolute densities in the intracellular fluid create a physicochemical condition called macromolecular crowding (MMC). Intracellular MMC entropically maintains the biochemical ...

However, whether BCAS2 has other functions within the nucleus remains largely unknown. Here, we show that BCAS2 is essential for primitive hematopoiesis in zebrafish and mouse embryos. The activation ...

Primary central nervous system (CNS) vasculitis is a rare, frequently misdiagnosed condition that affects the brain and ...

MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...

Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...