Hirota enthusiastically. Overall, the results suggest that dinuclear platinum(II) complexes could offer a more targeted approach to treating prostate cancer, specifically by inhibiting AR-mediated ...

Prostate cancer, especially in advanced stages such as castration-resistant prostate cancer, is challenging to treat.

Prostate cancer remains a global health challenge, ranking as the second most commonly diagnosed cancer among men. Although ...

The dinuclear platinum(II) complexes inhibit prostate cancer cell growth by binding to the androgen receptor (AR) and disrupting AR-mediated gene expression. This mechanism leads to apoptosis and ...

The team used a variety of methods to evaluate androgen receptor dynamics and therapeutic effects in LNCaP prostate cancer ...