Telomerase is an enzyme that can compensate for this shortening by maintaining telomeres at a stable length, helping to protect chromosomes against degradation and fusion. Mutations that ...
Consider the enzyme telomerase, which is responsible for maintaining protective telomeres at the natural ends of chromosomes. Were telomerase to seal off a broken strand of DNA with a telomere ...
The three were honored for “for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase.” According to the Royal Swedish Academy, this year’s Nobel Prize in Physiology or ...
Our research in this area aims to understand how telomere-associated proteins protect and maintain telomeres. Key questions include how subunits of the telomerase enzyme contribute to activity, how ...
“So we had to roll up our sleeves, break open the cells and try and find out what this potential new enzyme was that was adding DNA. That was in 1984 and we published telomerase in 198 ...
Dr. Tollefsbol's laboratory is also interested in the epigenetic regulation of the gene that produces telomerase (hTERT) and in unraveling the mysteries of how this gene relates to cancer and aging.
CNIO Telomeres and Telomerase Group - Humanism and Science Foundation. Sergio Piñeiro is standing, second from left. Maria Blasco is fifth from the left, standing./ Laura M. Lombardia.