Researchers from the TEDDY study highlight how specific genetic and environmental factors may drive early autoimmunity linked to type 1 diabetes in children, emphasizing distinct patterns for ...

This meant, for example, uploading their DNA profiles to a third-party genealogy site to analyze what are known as “runs of homozygosity,” or ROH: long stretches where the DNA inherited from one’s ...

France's Center for Anthropobiology and Genomics discovered Throin was a male with a high amount of genetic homozygosity.

SNP arrays have the added advantage of the ability to identify polyploidy and long stretches of homozygosity that may represent consanguinity or uniparental disomy, associated with a risk for ...

The highest prevalence of C282Y homozygosity is 1:250, seen in populations of North European ancestry. Low circulating hepcidin due to decreased hepatic expression of hepcidin resulting from ...

Eight founder strains are being intercrossed, and their offspring are being inbred to homozygosity, essentially producing recombinant inbred lines containing three to seven alleles 20. Because of ...

Alpha-1-antitrypsin (a1AT) deficiency is caused by homozygosity for the a1AT mutant Z gene and occurs in 1 in 2,000 births. The Z mutation confers an abnormal conformation on the protein, resulting in ...

The analysis showed that Thorin had “high genetic homozygosity,” which indicates inbreeding in the lineage’s recent past. It also offers no evidence of interbreeding with modern humans of the time.