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DESTINY-Breast06研究全文见刊《NEJM》,改写晚期乳腺癌内分泌治疗耐药后命运
大约70%的晚期乳腺癌为激素受体阳性HER2阴性,主要依靠内分泌治疗和化疗。对于内分泌治疗耐药患者,虽然细胞周期蛋白依赖性激酶CDK4/6抑制剂有效,但是仍然可能发生耐药。乳腺癌命运第四交响曲(DESTINY-Breast04)研究已经证实,德曲妥珠 ...
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