Asparaginyl hydroxylation decreased ARD binding to FIH; the hydroxylation status of ARD proteins that are FIH accessible may regulate the amount of FIH available to hydroxylate HIF-α. It is now ...
PHDs hydroxylate a prolyl residue in the amino- and the carboxy-terminal oxygendependent degradation domains, which promotes von Hippel-Lindau-tumour-suppressor-dependent proteolysis and results ...
Taking inspiration from enzymes, chemists at the University of Illinois Urbana-Champaign developed a catalyst to simplify the synthesis of ethers, key functional components of many drugs, foods, ...