An isogenic cell line was created to model cancer patients with the echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusion oncogene and tested for its ...

To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...

For years, neuroscience research overlooked female subjects, creating a significant bias. Today, researchers actively ...

Fan, X., Mocchi, M., Pascuzzi, B., Xiao, J., Metzger, B.A., Mathura, R.K., Hacker, C., Adkinson, J.A., Bartoli, E., Elhassa, S., Watrous, A.J., Zhang, Y., Goodman, W ...

Two Types. Confocal microscopy reveals α-synuclein (green) and lipids (red) in three adjacent inclusions (left and right). The white arrows point to Type I inclusions loaded with lipids. Blue ...

Using iPS cells generated from a patient with a myeloid neoplasm caused by a rare chromosomal rearrangement between the MECOM ...

Sickness-induced sleep is a behavior conserved across species that promotes recovery from illness, yet the underlying mechanisms are poorly understood. Here, we show that interleukin-6-like cytokine ...

Axol Bioscience conducted a blinded study investigating eight reference compounds on an isogenic cortical tri-culture axoModel, via an Axion multi-electrode array (MEA) system to assess ...

“Our approach provides new insights on the role of SF3B1 of mutation in cancer and enables the generation of SF3B1 mutant cell lines in relevant cellular context,” the authors concluded. “It not only ...

the expression of many regulators crucial to HSC maintenance enhanced in MDS-HPCs compared to HPCs generated from isogenic ...

Ryvu Therapeutics (WSE: RVU), a clinical-stage drug discovery and development company focusing on novel small molecule therapies that address emerging targets in oncology, today reported financial ...