An isogenic cell line was created to model cancer patients with the echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusion oncogene and tested for its ...
“It not only provides a generalizable approach for isogenic cell line engineering but also reveals novel aspects of cancer biology.” ...
Using iPS cells generated from a patient with a myeloid neoplasm caused by a rare chromosomal rearrangement between the MECOM ...
In partnership with Sumitomo Pharma America, Inc., Axol Bioscience conducted a blinded study investigating eight reference compounds on an isogenic cortical tri-culture axoModel, via an Axion ...
Two Types. Confocal microscopy reveals α-synuclein (green) and lipids (red) in three adjacent inclusions (left and right). The white arrows point to Type I inclusions loaded with lipids. Blue ...
For years, neuroscience research overlooked female subjects, creating a significant bias. Today, researchers actively ...
University of Georgia, Athens, GA. PhD, Jan 2007 – Aug 2014, Major: Plant Breeding, Genetics, & Genomics. University of Georgia, Athens, GA. M.S., 1999 – Dec 2001 ...
Fan, X., Mocchi, M., Pascuzzi, B., Xiao, J., Metzger, B.A., Mathura, R.K., Hacker, C., Adkinson, J.A., Bartoli, E., Elhassa, S., Watrous, A.J., Zhang, Y., Goodman, W ...
To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...
Ryvu Therapeutics (WSE: RVU), a clinical-stage drug discovery and development company focusing on novel small molecule therapies that address emerging targets in oncology, today reported financial ...
the expression of many regulators crucial to HSC maintenance enhanced in MDS-HPCs compared to HPCs generated from isogenic ...