Researchers discovered that the mRNA modification m6A triggers rapid degradation, regulating protein production. This breakthrough could inform drug development to manage protein-related diseases.
Long before mRNA vaccines captured global attention during the COVID-19 pandemic, researchers were already exploring their ...
It couples the degradation of an mRNA directly to the proteins produced and is significantly faster and more efficient than previously known mechanisms for mRNA degradation. Crucially, this ...
Although much less is known about mRNA export, a fundamentally different mechanism may be at work. This may be because of the greater size of the cargo, as mRNAs are exported as large ...
Humans and chimpanzees share more than 95% of our genome, and yet we are remarkably different. A new study highlights the ...
More information: Tang Cam Phung Pham et al, The mitochondrial mRNA-stabilizing protein SLIRP regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms ...
Breakthrough infections, where individuals contract the disease despite vaccination, became a critical issue as variant viruses spread during the pandemic.
The Russian mRNA vaccine under development can be “personalised” based on the genetic analysis of each person’s tumour to ...
Russia’s mRNA cancer vaccine, launching in 2025, uses AI to personalise treatment, training the immune system to target cancer cells effectively.
"Our LNP was able to deliver an mRNA therapeutic that reduced maternal ... as well as understanding the mechanisms of how it gets to the placenta, a question still not fully answered.
A recent study by researchers at Institute of Science Tokyo reveals the pivotal role of tristetraprolin (TTP), an RNA-binding ...