Tissue Penetration: Consistent with the recently updated trial protocol, tissue Css levels were evaluated in addition to plasma Css levels. The 80 mg/day dose, in both treatment arms, achieved tissue ...
Objective: To determine the efficacy and tolerability of magnesium valproate as monotherapy in patients with partial or generalised epilepsy. Design and Setting: This was a nonblinded study ...
Safety and Tolerability: Overall, (Z)-endoxifen was well tolerated and target tissue Css levels were achieved without significant Grade 3–4 toxicities. Four gynecologic events were reported in ...