Claudin-1 (CLDN1) is a protein usually found nestled between epithelial cells — which cover internal and external body surfaces — helping to bind them. “It works like a zipper to keep two ...
Astellas Pharma's zolbetuximab – currently leading an expanding pack of drugs targeting claudin 18.2 – has shown efficacy in the first of a pair of phase 3 trials of gastric or ...
Other companies developing claudin 18.2-targeted therapies include China's Innovent Bio, which started dosing patients with its CD3xClaudin 18.2 bispecific antibody IBI389 in a phase 1 trial ...
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