Background/aims: Newborn resuscitation with pure oxygen may induce short- and long term pathological changes via oxidative stress. Oxygen can adversely affect all tissues of the body. We studied ...

Such findings suggest a temporal 'window of opportunity' for effective hyperoxic therapy. We found in a severe model of sepsis induced by cecal ligation and puncture in rats, a dose-related ...

A wish to alleviate tissue hypoxia underlies the common clinical use of hyperoxic ventilation in shock. Yet, this straightforward approach is met by skepticism that is based on the potential pro ...

Background and aims: We have recently shown that Dextromethorphan is neuroprotective against excitotoxic and hyperoxic-induced brain injury. Beside its antagonistic effect on the NMDA [N-methyl-D ...

Objectives To evaluate the efficiency of the interval hypoxic-hyperoxic training (Reoxy therapy) in the rehabilitation of patients with osteoarthritis (OA) and post-COVID syndrome. Methods 36 patients ...

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Mitochondria play a significant and varied role in inflammatory lung disorders. Mitochondria, known as the powerhouse of the cell because of their role in producing energy, are now recognized as ...

Performance in athletic activities that include a significant aerobic component at mild or moderate altitudes shows a large individual variation. Physiologically, a large portion of the negative ...

This is generally a well-designed and carefully conducted study that is likely to be of interest to many both inside and outside of the field of lung tumorigenesis and normal lung development and ...

This accelerated radiotherapy is combined with inhalation of hyperoxic gas to decrease diffusion-limited hypoxia, and nicotinamide, a vasoactive agent, to decrease perfusion-limited hypoxia.

94 95 DIZE has been shown to reduce the severity of inflammation and oxidative stress from hyperoxic lung injury, most likely by increasing ACE2 activity by promoting MAS inhibition of DABK.96 DIZE ...