Efforts to contain the spread of SARS-CoV-2 may benefit from a new analytical tool developed by a team led by biologists at Boston College, who report their computer simulation of molecular ...

The subsequent experiments demonstrated that the virus indeed is capable of binding to cholesterol ... this happens only in the presence of viable ACE2 molecules on the surface of cellular membranes.

As suggested by their binding epitopes, only Ab59 showed a reduction of virus titers. FIGURE 2: Neutralization assays identify one monoclonal as blocking the ACE2-Spike protein ... [+] interaction.

These proteins undergo various modifications, including the addition of carbohydrate molecules ... the mouse version of the ACE2 protein does not bind to the SARS-CoV-2 spike, providing a clear ...