Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's ...

Ke Hou generated a compound that prevents tau aggregation in the murine brain, but the potential Alzheimer’s disease therapy ...

It is caused by the buildup of toxic proteins called amyloid fibrils throughout the body. The amyloid fibrils damage tissues ...

Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to ...

The kinetics of fibrillization in dilute aqueous solutions of the protein was monitored as a function of incubation time using the dye thioflavin T, which binds to amyloid fibrils but not to ...

Light chain amyloidosis is caused by plasma cells in the bone marrow that produce more light chain proteins than heavy chain proteins, which ultimately leads to the deposition of amyloid fibrils ...

Amyloid beta, TDP-43, and SOD-1 PFFs. These products support and accelerate the development of reliable neurodegenerative disease models. Tau TAU-H5115 Human Tau-441/2N4R Pre-formed Fibrils ...

The clinical experience at BUMC further illustrates the robust association between AL amyloid or LCDD and the dual findings of Bence Jones proteinuria and heavy albuminuria. All 6 of the patients ...

His lab is also exploring the efficacy of the curry spice extract, curcumin, to control inflammation and oxidative damage and to act directly on insoluble amyloid fibrils in plaques and more soluble ...

Leqembi selectively binds to soluble Aß aggregates (protofibrils), as well as insoluble Aß aggregates (fibrils) which are a major component ... and insoluble forms of amyloid-beta (Aß). Lecanemab is ...