Background Cystic fibrosis (CF) lung disease is defined by large numbers of neutrophils and associated damaging products in the airway. Delayed neutrophil apoptosis is described in CF although it is ...

The expression of RAGE-NOX2/4 axis proteins was analyzed using western blotting and immunofluorescence, while neuronal apoptosis was assessed with TUNEL staining. Furthermore, after performing quality ...

Physiological roles of cell competition in vertebrates and the universal mechanisms regulating diverse cell competition are unknown. Here, authors show that Foxo3-mediated physiological cell ...

Eosinophil apoptosis was suppressed by Mcl-1 overexpression ... or DAPI staining was used to identify viable, apoptotic and necrotic bmEos. Western blotting was performed as described.1 8 9 Data ...

Rapamycin enhances whole gland homeostasis and alleviates irradiation-induced parotid injury suggests a study published in ...

The accumulation of lipids in hepatocytes in nonalcoholic fatty liver disease (NAFLD) leads to an increase in reactive oxygen species and changes in the intracellular microenvironment, while ...

Functional enrichment analysis and Kaplan-Meier survival analysis were performed for differentially expressed genes. Western blot, Clone formation assay, Transwell assay and CCK-8 assay were performed ...

Is there ongoing apoptosis of ß-cells, and, if so, is this caused by aberrant genetic programming or something bad that invades the ß-cell's microenvironment? Type 2 diabetes is characterized as ...

By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...

Scale bar =100µm. c) Schematic representation of the IMQ-induced psoriasis mouse model. d) Representative images and statistical analysis of western blot analysis showing the expression of GSDMD and ...