These lipid-laden macrophages cause immunosuppression ... Inhibiting the protein CD36 with sulfosuccinimidyl oleate (SSO) prevented the uptake of myelin debris, whereas blockade of the lipid ...
A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote ...
Oxidative modification of photoreceptor disk proteins or membrane lipids may also be involved in recognition of damaged disks by RPE cell CD36 receptors that mediate endocytosis of ROS tips (15). In ...
These cells deal with microbes and repair tissue damage. Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular ...
The proposed mechanisms of action of some of the nutraceutical supplements on the mammalian cholesterol pathway are shown in Figure 2. Virtually all studies have shown very high safety profiles ...
platelets express defined immune receptors on their surface and secrete prestored cytokines and chemokines from their granules and thus also attract other immune cells such as macrophages ...
Metabolic adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments ... Transfer of cell-surface antigens by scavenger receptor CD36 promotes thymic tegulatory T cell ...