The boards of directors of Hookipa Pharma (HOOK) and Poolbeg Pharma announced that they have entered into non-binding ...
Cytokine release syndrome (CRS): a condition that occurs when the body overreacts to immunotherapy, which can become life-threatening if not treated immediately. ECOG performance status: a measurement ...
Complete responses (CRs) were seen in 43% ... and is associated with low responses to conventional therapies, including immunotherapy in particular," Danilov said during a press briefing at ...
An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that ...
Dr. Koffman has had no major side effects since the first five weeks of the trial when researchers were still figuring out the proper dosage and countering cytokine release syndrome (CRS ...
Vir Biotechnology's Phase 1 trials reveal promising safety and efficacy for dual-masked T-cell engagers targeting HER2 and ...
NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN WHOLE OR IN PART IN, INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD ...
KVA12123 is a VISTA-blocking immunotherapy in development as a monoclonal ... models or induction of cytokine release syndrome (CRS) in human clinical trials. Through the combination of unique ...
The results of this animal study support development of POLB 001 in a Phase 2 clinical study as a prophylactic for the prevention of immunotherapy-induced CRS. The previous successful LPS trial in ...
KVA12123 is a VISTA-blocking immunotherapy in development as a monoclonal ... inhibition in preclinical models without evidence of CRS in clinical trial participants. KVA12123 has been shown ...